Sayfullo comes from Nurata, one of the main centers of traditional Uzbek embroidery where the culture of nomads mixed with the sedentary population and created a rich intermingling of traditions that remains very strong today. He was taught his skill by the women of his family and, by an early age, he was knowledgeable about the ancient designs and their symbolism, techniques and methods of natural dying, cloth making, and suzani production.

The techniques of production can be learned by many, but Sayfullo goes beyond technique and puts his heart into every piece as if each were being produced for his very own family. His work is unique in that he specializes in designs from Nurata which differ significantly from those of other regions.